Description

n-[3-Chloro-4-(2-Pyrimidinyloxy)Phenyl]-4-Methoxybenzenesulfonamide CAS NO 338413-19-7 is a high-purity, advanced pharmaceutical intermediate characterized by its specific sulfonamide and pyrimidine functional groups. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily required by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or reagent in proteomics and enzyme inhibition studies.
• Agrochemical Development: Investigated as a precursor for novel herbicides or plant growth regulators due to its heterocyclic structure.
• Material Science: Potential application in the development of specialty polymers or organic electronic materials.
• Contract Synthesis: Supplied to CDMOs for custom synthesis and scale-up projects under cGMP guidelines.

Basic Information

Item	Details
Product Name	n-[3-Chloro-4-(2-Pyrimidinyloxy)Phenyl]-4-Methoxybenzenesulfonamide
CAS No.	338413-19-7
Molecular Formula	C17H14ClN3O4S
Molecular Weight	391.83 g/mol
Synonyms	4-Methoxy-N-[3-chloro-4-(pyrimidin-2-yloxy)phenyl]benzenesulfonamide; 338413-19-7; 4-Methoxybenzenesulfonamide, N-[3-chloro-4-(2-pyrimidinyloxy)phenyl]-; N-(3-Chloro-4-(pyrimidin-2-yloxy)phenyl)-4-methoxybenzenesulfonamide; 4-Methoxy-N-(3-chloro-4-(pyrimidin-2-yloxy)phenyl)benzenesulfonamide; 2-Pyrimidinyloxy phenyl sulfonamide derivative; 3-Chloro-4-(2-pyrimidinyloxy)phenyl sulfonamide
EINECS	Contact for details

Quality Control

Our n-[3-Chloro-4-(2-Pyrimidinyloxy)Phenyl]-4-Methoxybenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, including ICH guidelines for stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.