Description

4-Chloro-1-Naphthyl 5-Methoxy-2-(2-Pyridinyl)-4-Pyrimidinyl Ether is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those with pyrimidine and naphthalene core structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with optimized biological activity and pharmacokinetic properties.
• Kinase Inhibitor Development: Serves as a precursor or core scaffold in the research of protein kinase inhibitors, a major class of therapeutics for cancer and inflammatory diseases.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value organic compounds.
• Academic & Institutional R&D: Utilized in university and government research laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-1-Naphthyl 5-Methoxy-2-(2-Pyridinyl)-4-Pyrimidinyl Ether
CAS No.	338410-61-0
Molecular Formula	C20H14ClN3O2
Molecular Weight	363.80 g/mol
Synonyms	4-Chloro-1-naphthyl 5-methoxy-2-(pyridin-2-yl)pyrimidin-4-yl ether; 5-Methoxy-2-(2-pyridinyl)-4-(4-chloro-1-naphthyloxy)pyrimidine; 4-(4-Chloro-1-naphthyloxy)-5-methoxy-2-(2-pyridinyl)pyrimidine; 338410-61-0; 4-Chloro-1-naphthalenyl 5-methoxy-2-(2-pyridinyl)-4-pyrimidinyl ether
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Naphthyl 5-Methoxy-2-(2-Pyridinyl)-4-Pyrimidinyl Ether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be handled as a light-sensitive and moisture-sensitive material. Keep away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.