Description

1-[[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl](Methyl)Amino]-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of agrochemicals and specialty fine chemicals. The precise functional groups present in its structure make it a valuable scaffold for creating compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of new drug candidates, especially for targeted therapies.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its pyridine and pyrimidine motifs.
• Chemical Synthesis Building Block: Employed in organic synthesis to construct complex nitrogen-containing heterocycles for various R&D applications.
• Biochemical Probe Development: Utilized in life sciences research to create molecular probes for studying enzyme interactions and biological pathways.
• Material Science Research: Investigated for potential use in creating specialty polymers or organic electronic materials due to its conjugated system.

Basic Information

Item	Details
Product Name	1-[[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl](Methyl)Amino]-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	338399-20-5
Molecular Formula	C12H6ClF3N5O2
Molecular Weight	345.66 g/mol
Synonyms	5-Pyrimidinecarbonitrile, 1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methylamino]-2,4-dihydro-2,4-dioxo-; 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; CAS 338399-20-5; 1-[(3-Chloro-5-trifluoromethyl-2-pyridyl)-methyl-amino]-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-[[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl](Methyl)Amino]-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting R&D and process standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.