Description

1-(3-Methoxypropyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in antiviral and oncology research. It is essential for R&D laboratories and production facilities focused on developing novel nucleoside analogs and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel antiviral and anticancer drug candidates.
• Nucleoside Analog Research: Serves as a modified pyrimidine base precursor for the development of new therapeutic nucleosides.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds with potential biological activity.
• Biochemical Research: Employed in studies investigating enzyme inhibition and metabolic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of target APIs.

Basic Information

Product Name	1-(3-Methoxypropyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	338399-18-1
Molecular Formula	C9H11N3O3
Molecular Weight	209.20 g/mol
Synonyms	5-Cyano-1-(3-methoxypropyl)dihydrouracil; 1-(3-Methoxypropyl)-5-cyanodihydrouracil; 5-Cyano-1-(3-methoxypropyl)-2,4-dihydroxypyrimidine; 1-(3-Methoxypropyl)dihydro-5-cyanouracil; 2,4-Dioxo-1-(3-methoxypropyl)-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 1,2,3,4-tetrahydro-1-(3-methoxypropyl)-2,4-dioxo-
EINECS	Contact for details

Quality Control

Our 1-(3-Methoxypropyl)-2,4-Dioxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.