Description

3-(4-Aminobenzylthio)Benzotrifluoride is a high-value trifluoromethylated aromatic amine building block, essential for introducing specific steric and electronic properties into advanced molecular architectures. Its core value lies in enabling the synthesis of complex, functionalized compounds with enhanced biological activity and material characteristics. This intermediate is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring trifluoromethyl groups for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the benzotrifluoride moiety contributes to efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for functional organic materials used in display technologies and electronic devices.
• Polymer Modification: Employed to introduce aromatic amine and sulfur functionalities into polymer backbones, altering thermal and mechanical properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized colorants and fluorescent markers.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	3-(4-Aminobenzylthio)Benzotrifluoride
CAS No.	338398-58-6
Molecular Formula	C14H12F3NS
Molecular Weight	283.31 g/mol
Synonyms	3-[(4-Aminophenyl)methylthio]benzotrifluoride; 3-[(4-Aminobenzyl)thio]benzotrifluoride; 1-Amino-4-[(3-trifluoromethylphenyl)thiomethyl]benzene; 4-[(3-Trifluoromethylphenyl)thiomethyl]aniline; [4-(3-Trifluoromethylphenylsulfanylmethyl)phenyl]amine; 3-(4-Aminobenzylmercapto)benzotrifluoride; α-(3-Trifluoromethylthiophenyl)-p-toluidine (related structure)
EINECS	Contact for details

Quality Control

Our 3-(4-Aminobenzylthio)Benzotrifluoride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting R&D and production standards. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.