Description

6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinol is a high-purity, heterocyclic organic compound featuring a pyrimidine core functionalized with pyridinyl and phenylsulfonylmethyl groups. This molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of small-molecule drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study biological pathways and validate novel drug targets.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses due to its reactive functional groups, enabling further chemical modifications.
• Reference Standard: Supplied as a high-purity material for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinol
CAS No.	337923-71-4
Molecular Formula	C₁₆H₁₃N₃O₃S
Molecular Weight	327.36 g/mol
Synonyms	6-[(Phenylsulfonyl)methyl]-2-(4-pyridinyl)-4(3H)-pyrimidinone; 2-(Pyridin-4-yl)-6-[(phenylsulfonyl)methyl]pyrimidin-4-ol; 4-Pyrimidinol, 6-[(phenylsulfonyl)methyl]-2-(4-pyridinyl)-; CAS 337923-71-4; 6-(Phenylsulfonylmethyl)-2-(4-pyridyl)-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 6-[(Phenylsulfonyl)Methyl]-2-(4-Pyridinyl)-4-Pyrimidinol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.