Description

1-Cyclopropyl-7-(4-Dithiocarboxylatopiperazin-1-Yl)-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate CAS NO 336879-89-1 is a high-purity, advanced pharmaceutical intermediate belonging to the fluoroquinolone class. This compound is valued for its role as a critical building block in the synthesis of novel antibacterial agents, offering researchers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D departments, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of next-generation fluoroquinolone antibiotics.
• Antibacterial Agent Synthesis: Used in the synthetic pathway for creating novel compounds targeting resistant bacterial strains.
• Biochemical Research: Serves as a reference standard or a substrate in enzymatic and receptor-binding studies related to bacterial DNA gyrase and topoisomerase IV.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities within pharmaceutical manufacturing.
• Academic Research: Utilized in universities and research institutes for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting point for the custom synthesis of labeled compounds (e.g., deuterated, C14) for pharmacokinetic and metabolic studies.

Basic Information

Product Name	1-Cyclopropyl-7-(4-Dithiocarboxylatopiperazin-1-Yl)-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	336879-89-1
Molecular Formula	C19H19FN4O3S2
Molecular Weight	434.51 g/mol
Synonyms	7-(4-Dithiocarboxylatopiperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid dithiocarboxylate derivative; Quinolone dithiocarboxylate intermediate; Fluoroquinolone piperazine derivative; CAS 336879-89-1; 1-Cyclopropyl-7-(4-dithiocarboxy-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-piperazinyl)-3-quinolinecarboxylic acid, dithiocarboxylic acid ester
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-7-(4-Dithiocarboxylatopiperazin-1-Yl)-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.