Description

L-β-Homo-Asp-Oh.Hcl is a high-purity, non-proteinogenic amino acid derivative, specifically an L-configured homologue of aspartic acid. This compound is a critical building block in advanced peptide synthesis and pharmaceutical research, offering unique structural properties for modifying peptide backbones. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require specialized amino acids for drug discovery, peptide engineering, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Research & Synthesis: Used to introduce structural modifications and enhance metabolic stability, bioavailability, or receptor selectivity in custom peptides.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a probe for investigating protein structure-function relationships.
• Drug Discovery: Employed in medicinal chemistry for creating libraries of compounds with potential biological activity.
• Bioconjugation: Can be utilized for labeling peptides or proteins due to its carboxylic acid functionality.

Basic Information

Product Name	L-β-Homo-Asp-Oh.Hcl
CAS No.	336182-10-6
Molecular Formula	C5H10ClNO4
Molecular Weight	183.59 g/mol
Synonyms	L-β-Homoaspartic acid hydrochloride; (S)-2-Amino-3-(carboxymethyl)propanoic acid hydrochloride; L-3-Aminobutane-1,4-dioic acid hydrochloride; H-Asp(β-CH2)-OH·HCl; L-Homo-Asp-OH·HCl; β-Homo-L-aspartic acid HCl; (2S)-2-Azaniumyl-4-carboxybutanoate chloride
EINECS	Contact for details

Quality Control

Our L-β-Homo-Asp-Oh.Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]D20: Specific range provided on COA
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.