Description

L-Norleucine, 6-(Aminooxy)- (9Ci) is a specialized, non-proteinogenic amino acid derivative featuring a reactive aminooxy functional group. This unique structure makes it a valuable building block in organic synthesis and bioconjugation chemistry, particularly for the site-specific modification of biomolecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutics, diagnostics, and research tools.

Application

• Bioconjugation Reagent: Used for the site-specific labeling of proteins, peptides, and antibodies via oxime ligation, a critical technique in antibody-drug conjugate (ADC) development and diagnostic probe synthesis.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor for novel drug candidates, especially in oncology and targeted therapy research.
• Chemical Biology Probe: Enables the study of protein function and interaction through the introduction of stable linkages and reporter tags.
• Peptide Synthesis: Incorporated into custom peptides to introduce unique chemical handles or alter physicochemical properties for research purposes.
• Material Science: Potential use in the surface functionalization of biomaterials and nanoparticles for targeted delivery applications.

Basic Information

Product Name	L-Norleucine, 6-(Aminooxy)- (9Ci)
CAS No.	335341-56-5
Molecular Formula	C6H14N2O3
Molecular Weight	162.19 g/mol
Synonyms	(S)-2-Amino-6-(aminooxy)hexanoic acid; 6-Aminooxy-L-norleucine; L-2-Amino-6-aminooxycaproic acid; (S)-2-Amino-6-aminooxyhexanoic acid; Aminooxy-norleucine; Norleucine, 6-(aminooxy)-, L-; 6-(Aminooxy)-L-norleucine
EINECS	Contact for details

Quality Control

We supply L-Norleucine, 6-(Aminooxy)- (9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict GMP principles in our handling and documentation to ensure traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.