Description

2,3',4',5'-Tetrafluorobiphenyl-4-Ol is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique polyfluorinated aromatic structure, which is essential for imparting specific electronic and steric properties to target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as by material scientists working on specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine atoms improve lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a core component in the development of fluorinated liquid crystals for high-performance displays and optical devices.
• Organic Electronic Materials: Intermediate in the synthesis of organic semiconductors, hole-transport materials, and other components for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl architectures.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, material science, and general organic synthesis research in academic and industrial laboratories.

Basic Information

Product Name	2,3',4',5'-Tetrafluorobiphenyl-4-Ol
CAS No.	335125-98-9
Molecular Formula	C12H6F4O
Molecular Weight	242.17 g/mol
Synonyms	4-Hydroxy-2,3',4',5'-tetrafluorobiphenyl; [1,1'-Biphenyl]-4-ol, 2,3',4',5'-tetrafluoro-; 2,3',4',5'-Tetrafluoro[1,1'-biphenyl]-4-ol; 2,3',4',5'-Tetrafluoro-4-biphenylol; Tetrafluorobiphenylol; Polyfluorinated Biphenylol Intermediate
EINECS	Contact for details

Quality Control

Our 2,3',4',5'-Tetrafluorobiphenyl-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.