Description

(4-Difluoromethyl-6-Phenyl-Pyrimidin-2-Ylsulfanyl)-Acetic Acid is a specialized pyrimidine derivative featuring a difluoromethyl group and a thioacetic acid side chain, making it a valuable synthetic intermediate. This compound is significant for its role in the development of advanced chemical entities, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the pyrimidine core.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and functionalized materials in custom synthesis projects.
• Ligand and Catalyst Development: The sulfur and nitrogen donor atoms make it a candidate for designing novel ligands in coordination chemistry and catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways due to its modifiable structure.

Basic Information

Product Name	(4-Difluoromethyl-6-Phenyl-Pyrimidin-2-Ylsulfanyl)-Acetic Acid
CAS No.	333429-71-3
Molecular Formula	C₁₃H₁₀F₂N₂O₂S
Molecular Weight	296.29 g/mol
Synonyms	2-[(4-Difluoromethyl-6-phenylpyrimidin-2-yl)sulfanyl]acetic acid; [(4-Difluoromethyl-6-phenyl-2-pyrimidinyl)thio]acetic acid; Acetic acid, 2-[(4-difluoromethyl-6-phenyl-2-pyrimidinyl)thio]-; (4-Difluoromethyl-6-phenyl-pyrimidin-2-ylsulfanyl)-acetic acid; 333429-71-3; 4-Difluoromethyl-6-phenyl-2-pyrimidinethiol acetate derivative
EINECS	Contact for details

Quality Control

Our (4-Difluoromethyl-6-Phenyl-Pyrimidin-2-Ylsulfanyl)-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.