Description

3-(4,6-Diamino-Pyrimidin-2-Ylsulfanyl)-Propionic Acid is a high-purity, functionalized pyrimidine derivative designed for advanced chemical synthesis. This compound serves as a critical versatile building block for pharmaceutical research and fine chemical manufacturing, offering a reactive thioether linkage and a carboxylic acid group for further derivatization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the pyrimidine core is pharmacologically active.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Chelator Development: Utilized in creating specialized ligands for catalysis or metal ion chelation due to its diamino-pyrimidine moiety.
• Peptide Mimetics and Bioconjugation: The propionic acid side chain enables coupling to amines, facilitating its use in creating peptide analogs or bioconjugation linkers.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Used to create activity-based probes or labeled compounds for studying biological pathways.

Basic Information

Product Name	3-(4,6-Diamino-Pyrimidin-2-Ylsulfanyl)-Propionic Acid
CAS No.	333409-96-4
Molecular Formula	C7H10N4O2S
Molecular Weight	214.24 g/mol
Synonyms	2-[(4,6-Diamino-2-pyrimidinyl)thio]propanoic Acid; 3-[(4,6-Diaminopyrimidin-2-yl)sulfanyl]propanoic Acid; 4,6-Diamino-2-mercaptopyrimidine-3-propionic Acid; 333409-96-4; Propanoic acid, 2-[(4,6-diamino-2-pyrimidinyl)thio]-; DA-Pyrimidine-Thio-Prop Acid
EINECS	Contact for details

Quality Control

Our 3-(4,6-Diamino-Pyrimidin-2-Ylsulfanyl)-Propionic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.