Description

Benzamide, n-[1-(2,3-Di-o-Acetyl-β-D-Arabinofuranosyl)-1,2-Dihydro-2-Oxo-4-Pyrimidinyl]- is a high-purity nucleoside derivative building block of significant interest in advanced pharmaceutical research and development. This compound is crucial for the synthesis of modified oligonucleotides and potential antiviral or anticancer agents, offering researchers a precise tool for probing biological mechanisms. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors. The material is supplied with comprehensive analytical documentation to ensure reliability and reproducibility in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel nucleoside-based therapeutics, including potential antiviral and anticancer drugs.
• Antisense Oligonucleotide Synthesis: Used as a modified building block (phosphoramidite) for the solid-phase synthesis of oligonucleotides for research and therapeutic applications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Process Chemistry & Scale-Up: Provides a defined starting material for optimizing synthetic routes and scaling up the production of active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	Benzamide, n-[1-(2,3-Di-o-Acetyl-β-D-Arabinofuranosyl)-1,2-Dihydro-2-Oxo-4-Pyrimidinyl]-
CAS No.	332863-97-5
Molecular Formula	C20H21N3O8
Molecular Weight	431.40 g/mol
Synonyms	1-(2,3-Di-O-acetyl-β-D-arabinofuranosyl)-N-benzoylcytosine; N-Benzoyl-1-(2,3-di-O-acetyl-β-D-arabinofuranosyl)cytosine; 1-(2,3-Di-O-acetyl-β-D-arabinofuranosyl)-N4-benzoylcytosine; Bz-arac; N4-Benzoyl-1-(2,3-di-O-acetyl-β-D-arabinofuranosyl)cytosine; Ara-C Benzoyl Protected Intermediate; Cytarabine Benzoyl Derivative
EINECS	Contact for details

Quality Control

Every batch of Benzamide, n-[1-(2,3-Di-o-Acetyl-β-D-Arabinofuranosyl)-1,2-Dihydro-2-Oxo-4-Pyrimidinyl]- is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research. Our quality commitment includes identity confirmation, purity assessment by HPLC, and control of specified impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.