Description

5-(4-Bromo-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of novel heterocyclic scaffolds with targeted biological activity. It serves as a key building block for scientists and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities within the pyrazolopyrimidine class.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection products, such as herbicides and fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services for complex molecules.

Basic Information

Product Name	5-(4-Bromo-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester
CAS No.	332856-77-6
Molecular Formula	C₁₆H₁₅BrF₃N₃O₂
Molecular Weight	418.21 g/mol
Synonyms	Ethyl 5-(4-bromophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-(4-Bromophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; 332856-77-6; 5-(p-Bromophenyl)-7-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-(4-bromophenyl)-4,5,6,7-tetrahydro-7-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 5-(4-Bromo-Phenyl)-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.