Description

5-Benzo[1,3]Dioxol-5-Yl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization programs due to its fused pyrazolo-pyrimidine core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Biochemical Tool Compound: Potential use in developing probes for investigating specific biological pathways and enzyme inhibition.

Basic Information

Item	Details
Product Name	5-Benzo[1,3]Dioxol-5-Yl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	332856-52-7
Molecular Formula	C₁₅H₁₂F₃N₃O₄
Molecular Weight	355.27 g/mol
Synonyms	5-(1,3-Benzodioxol-5-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 5-(Benzo[d][1,3]dioxol-5-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 332856-52-7; Tetrahydro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 5-Benzo[1,3]Dioxol-5-Yl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.