Description

Ethyl 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the exploration of new pharmacophores in drug discovery programs.
• Process Development & Scale-up: Used in optimizing synthetic routes from laboratory scale to pilot plant and commercial manufacturing for new APIs.
• Reference Standard: Employed as an analytical standard for quality control, method development, and regulatory submissions in pharmaceutical analysis.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Product Name	Ethyl 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetate
CAS No.	332392-83-3
Molecular Formula	C21H22N2O4S2
Molecular Weight	430.54 g/mol
Synonyms	Ethyl [(3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetate; 2-(((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetic acid ethyl ester; Thienopyrimidine derivative intermediate; CAS 332392-83-3; 4H-Benzo[4,5]thieno[2,3-d]pyrimidin-4-one, 3-(4-methoxyphenyl)-2-[(carboxymethyl)thio]-5,6,7,8-tetrahydro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), related substances, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.