Description

Benzoic Acid, 5-Chloro-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is a specialized Fmoc-protected amino acid derivative, a crucial building block in modern solid-phase peptide synthesis (SPPS). Its value lies in enabling the controlled, high-purity assembly of complex peptide sequences for research and development. This compound is essential for pharmaceutical researchers, biochemists, and fine chemical manufacturers developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential addition of amino acids in automated peptide synthesizers.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs, hormones, and therapeutic agents.
• Bioconjugation: Serves as a precursor for creating peptide-protein conjugates, antibody-drug conjugates (ADCs), and other bioconjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Biochemical Research: Utilized in academic and industrial laboratories for studying protein structure, function, and interactions.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of more complex organic molecules.

Basic Information

Item	Details
Product Name	Benzoic Acid, 5-Chloro-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci)
CAS No.	332121-90-1
Molecular Formula	C22H16ClNO4
Molecular Weight	393.82 g/mol
Synonyms	Fmoc-2-Amino-5-chlorobenzoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-chloroanthranilic acid; 5-Chloro-2-[(9-fluorenylmethoxycarbonyl)amino]benzoic acid; 2-[(Fmoc)amino]-5-chlorobenzoic acid; Fmoc-5-Cl-2-Abz-OH; Fmoc-2-Abz(5-Cl)-OH; N-Fmoc-5-chloroanthranilic acid; 5-Chloro-N-Fmoc-anthranilic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Chloro-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, critical for sensitive peptide synthesis applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.