Description

2-[(7-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4-Ol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational drug candidates, especially kinase inhibitors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Serves as a reference standard or a tool compound for biological target validation and assay development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-[(7-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4-Ol
CAS No.	332074-13-2
Molecular Formula	C₁₅H₁₅N₅O₂
Molecular Weight	297.31 g/mol
Synonyms	2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-6-methyl-4(3H)-pyrimidinone; 6-Methyl-2-[(7-methoxy-4-methylquinazolin-2-yl)amino]pyrimidin-4-ol; 2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-6-methylpyrimidin-4-ol; 332074-13-2; 4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-6-methyl-; CAS 332074-13-2
EINECS	Contact for details

Quality Control

Our 2-[(7-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Methylpyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.