Description

(S)-3-Amino-5-Hexynoic Acid Hydrochloride is a high-purity chiral building block and amino acid derivative, essential for advanced pharmaceutical and biochemical research. Its value lies in its role as a key intermediate for synthesizing complex molecules with specific stereochemistry, enabling the development of targeted therapeutics and bioactive compounds. This product is critically needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and neurology.
• Peptidomimetics & Conformationally Restricted Peptides: Used to introduce alkyne functionality and chiral centers into peptide backbones, modifying biological activity and stability.
• Bioconjugation & Click Chemistry: The terminal alkyne group serves as a handle for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to label or link biomolecules.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks.
• Agrochemical Research: Acts as a building block for creating novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Academic & Institutional Research: Serves as a standard or reagent in university and government labs studying amino acid metabolism, enzyme inhibition, and molecular recognition.

Basic Information

Product Name	(S)-3-Amino-5-Hexynoic Acid Hydrochloride
CAS No.	332064-85-4
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	(S)-3-Amino-5-hexynoic acid HCl; (3S)-3-Amino-5-hexynoic acid hydrochloride; (S)-3-Aminohex-5-ynoic acid hydrochloride; L-3-Amino-5-hexynoic acid hydrochloride; (S)-3-Amino-5-hexynoate hydrochloride; 5-Hexynoic acid, 3-amino-, hydrochloride, (3S)-; 332064-85-4; A chiral γ-amino alkyne acid derivative
EINECS	Contact for details

Quality Control

Every batch of (S)-3-Amino-5-Hexynoic Acid Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development under cGMP guidelines. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.