Description

(S)-Fmoc-Gamma γ-Diphenyl-β-Homo CAS NO 332062-08-5 is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This compound is a critical building block for constructing complex peptide chains with specific stereochemistry, enabling the development of novel therapeutics and biochemical tools. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, facilitating the controlled assembly of complex peptides.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Bioconjugation & Probe Development: Used to incorporate unique, bulky side chains into peptides for creating targeted probes, diagnostic agents, or drug conjugates.
• Structure-Activity Relationship (SAR) Studies: Enables medicinal chemists to explore the impact of specific, constrained amino acid structures on biological activity and peptide stability.
• Peptidomimetic Research: Essential for designing and synthesizing peptide mimics that resist enzymatic degradation while maintaining biological function.

Basic Information

Product Name	(S)-Fmoc-Gamma γ-Diphenyl-β-Homo
CAS No.	332062-08-5
Molecular Formula	C31H27NO4
Molecular Weight	477.55 g/mol
Synonyms	(S)-9-Fluorenylmethyloxycarbonyl-γ,γ-diphenyl-β-homoalanine; Fmoc-(S)-γ,γ-Diphenyl-β-homoAla-OH; (S)-Fmoc-γ,γ-Diphenyl-β-homoalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-γ,γ-diphenyl-L-β-homoalanine; Fmoc-Diphenyl-β-homoalanine; Fmoc-γ,γ-Diphenyl-β-hAla-OH; CAS 332062-08-5
EINECS	Contact for details

Quality Control

Our (S)-Fmoc-Gamma γ-Diphenyl-β-Homo is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification, to ensure it meets the stringent requirements for advanced research and cGMP-grade synthesis. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.