Description

Ethyl 2-(8-Bromo-7-(4-Chlorobenzyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-1-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the purine derivative class. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting various disease pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential adenosine receptor antagonists and other purine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new molecules with optimized pharmacological profiles.
• API Development: Serves as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition and receptor-ligand interactions.
• Academic & Institutional Research: Employed in university and research institute laboratories for exploratory synthetic projects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	Ethyl 2-(8-Bromo-7-(4-Chlorobenzyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-1-Yl)Acetate
CAS No.	331840-01-8
Molecular Formula	C₁₇H₁₆BrClN₄O₄
Molecular Weight	455.69 g/mol
Synonyms	1H-Purine-1-acetic acid, 8-bromo-7-[(4-chlorophenyl)methyl]-2,3,6,7-tetrahydro-3-methyl-2,6-dioxo-, ethyl ester; Ethyl 8-Bromo-7-(4-chlorobenzyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-1-acetate; 331840-01-8; 8-Bromo-7-(4-chlorobenzyl)-3-methyl-1-(2-ethoxy-2-oxoethyl)-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(8-Bromo-7-(4-Chlorobenzyl)-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-1-Yl)Acetate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.