Description

Ethyl 2-({7-[3-(4-Bromophenoxy)-2-Hydroxypropyl]-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl}Sulfanyl)Propanoate is a high-purity, advanced pharmaceutical intermediate with a complex purine-based structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and immunology. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted, small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel purine-based drug candidates targeting specific cellular pathways.
• Oncology Research: Used in the development of potential anti-cancer agents due to its modifiable purine scaffold, which can interact with various kinase enzymes.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and mechanism-of-action studies.
• API Development: Employed in the process development and scale-up of Active Pharmaceutical Ingredients (APIs) with complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client drug discovery programs.

Basic Information

Product Name	Ethyl 2-({7-[3-(4-Bromophenoxy)-2-Hydroxypropyl]-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl}Sulfanyl)Propanoate
CAS No.	331726-28-4
Molecular Formula	C20H23BrN4O5S
Molecular Weight	511.39 g/mol
Synonyms	Ethyl 2-[(7-{3-[(4-Bromophenyl)oxy]-2-hydroxypropyl}-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)thio]propanoate; 8-[(1-Ethoxycarbonyl)ethylthio]-7-[3-(4-bromophenoxy)-2-hydroxypropyl]-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 331726-28-4; Purine-2,6-dione derivative; Bromophenoxypropyl purine thioether ester.
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-({7-[3-(4-Bromophenoxy)-2-Hydroxypropyl]-3-Methyl-2,6-Dioxo-2,3,6,7-Tetrahydro-1H-Purin-8-Yl}Sulfanyl)Propanoate adheres to stringent quality management systems, ensuring batch-to-batch consistency for research and development. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and MS to guarantee the high purity and structural integrity required for sensitive pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.