Description

4-Pyrimidinecarboxylicacid,6-(2-Fluorophenyl)-1,2,3,6-Tetrahydro-5-Methyl-2-Oxo-,Methylester(9Ci) is a high-purity, synthetically valuable pyrimidine derivative. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized pyrimidine core and fluorophenyl moiety.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial material production.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	4-Pyrimidinecarboxylicacid,6-(2-Fluorophenyl)-1,2,3,6-Tetrahydro-5-Methyl-2-Oxo-,Methylester(9Ci)
CAS No.	331658-44-7
Molecular Formula	C14H13FN2O3
Molecular Weight	276.26 g/mol
Synonyms	Methyl 6-(2-fluorophenyl)-5-methyl-2-oxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate; 6-(2-Fluorophenyl)-1,2,3,6-tetrahydro-5-methyl-2-oxo-4-pyrimidinecarboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 6-(2-fluorophenyl)-1,2,3,6-tetrahydro-5-methyl-2-oxo-, methyl ester; 331658-44-7; Methyl 6-(o-fluorophenyl)-5-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development needs with custom purity grades and can provide documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.