Description

4-Pyrimidinecarboxylicacid,1,2,3,6-Tetrahydro-6-(2-Methoxyphenyl)-5-Methyl-2-Oxo-,Methylester(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by R&D chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates targeting specific biological pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a defined starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	4-Pyrimidinecarboxylicacid,1,2,3,6-Tetrahydro-6-(2-Methoxyphenyl)-5-Methyl-2-Oxo-,Methylester(9Ci)
CAS No.	331658-36-7
Molecular Formula	C15H16N2O4
Molecular Weight	288.30 g/mol
Synonyms	Methyl 1,2,3,6-tetrahydro-6-(2-methoxyphenyl)-5-methyl-2-oxo-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-6-(2-methoxyphenyl)-5-methyl-2-oxo-, methyl ester; Methyl 6-(2-methoxyphenyl)-5-methyl-2-oxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylate; 331658-36-7; 6-(2-Methoxyphenyl)-5-methyl-2-oxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and purity suitable for pharmaceutical R&D and scale-up. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with ICH guidelines for impurities and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.