Description

4-Pyrimidinecarboxylicacid,1,2,3,6-Tetrahydro-5-Methyl-2-Oxo-6-(3-Pyridinyl)-,Methylester(9Ci) is a high-purity, complex heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and research chemical. Its unique fused pyrimidine-pyridine structure makes it a valuable scaffold for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Institutional Research: Employed in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Process Development: Used in scaling up synthetic routes and optimizing manufacturing processes for related API candidates.

Basic Information

Product Name	4-Pyrimidinecarboxylicacid,1,2,3,6-Tetrahydro-5-Methyl-2-Oxo-6-(3-Pyridinyl)-,Methylester(9Ci)
CAS No.	331658-20-9
Molecular Formula	C12H13N3O3
Molecular Weight	247.25 g/mol
Synonyms	1,2,3,6-Tetrahydro-5-methyl-2-oxo-6-(3-pyridinyl)-4-pyrimidinecarboxylic acid methyl ester; Methyl 1,2,3,6-tetrahydro-5-methyl-2-oxo-6-(pyridin-3-yl)pyrimidine-4-carboxylate; 6-(3-Pyridinyl)-1,2,3,6-tetrahydro-5-methyl-2-oxo-4-pyrimidinecarboxylic acid methyl ester; CAS 331658-20-9; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-5-methyl-2-oxo-6-(3-pyridinyl)-, methyl ester; 6-(Pyridin-3-yl)-1,2,3,6-tetrahydro-5-methyl-2-oxopyrimidine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Pyrimidinecarboxylicacid,1,2,3,6-Tetrahydro-5-Methyl-2-Oxo-6-(3-Pyridinyl)-,Methylester(9Ci) adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for advanced applications, and our quality system is designed to meet the rigorous standards of global pharmaceutical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.