Description

5-Pyrimidinecarbonitrile, 1,6-Dihydro-2-(4-Morpholinyl)-6-Oxo-4-Phenyl- is a high-value, heterocyclic organic compound featuring a pyrimidine core substituted with a nitrile group and a morpholine ring. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry research. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of novel active compounds targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Synthesis Building Block: Employed in organic synthesis to construct complex heterocyclic systems due to its reactive nitrile and carbonyl functionalities.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Material Science Exploration: Investigated for use in the development of specialty chemicals and functional materials.

Basic Information

Item	Details
Product Name	5-Pyrimidinecarbonitrile, 1,6-Dihydro-2-(4-Morpholinyl)-6-Oxo-4-Phenyl-
CAS No.	331648-59-0
Molecular Formula	C15H14N4O2
Molecular Weight	282.30 g/mol
Synonyms	4-Phenyl-2-morpholino-6-oxo-1,6-dihydropyrimidine-5-carbonitrile; 2-Morpholino-4-phenyl-6-oxo-1,6-dihydropyrimidine-5-carbonitrile; 1,6-Dihydro-2-(4-morpholinyl)-6-oxo-4-phenyl-5-pyrimidinecarbonitrile; 331648-59-0; 4-Phenyl-2-morpholin-4-yl-6-oxo-1H-pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.