Description

5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating a pyrazolopyrimidine core and a carboxylic acid functional group. This compound is of significant commercial importance as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a specialized monomer or additive in the research of advanced polymers and organic electronic materials.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Synthesis: Utilized as a versatile building block for further functionalization, enabling the creation of diverse chemical libraries for screening.

Basic Information

Product Name	5-Methyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	331647-99-5
Molecular Formula	C9H5F3N4O2
Molecular Weight	258.16 g/mol
Synonyms	5-Methyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxylic acid; 7-(Trifluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-methyl-7-(trifluoromethyl)-; 331647-99-5; 5-Methyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP and ISO 9001 standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.