Description

Propan-2-Yl 4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, synthetically derived tetrahydropyrimidine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes for the production of proprietary APIs.
• Biochemical Research: Potential tool compound for studying enzyme inhibition and receptor binding activities in vitro.
• Fine Chemical Production: Building block for creating specialized, high-value chemicals used in agrochemicals and material science.

Basic Information

Product Name	Propan-2-Yl 4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	330848-49-2
Molecular Formula	C16H18N2O4
Molecular Weight	302.33 g/mol
Synonyms	Isopropyl 4-(3-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(3-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid isopropyl ester; 5-Carboxyisopropyl 4-(3-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine; DHPM derivative; Biginelli adduct; Tetrahydropyrimidinone derivative; CAS 330848-49-2
EINECS	Contact for details

Quality Control

Our production of Propan-2-Yl 4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light, heat, or air should be avoided. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.