Description

2-Methoxyethyl 6-Methyl-2-Oxo-4-(4-Propoxyphenyl)-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate is a high-purity, synthetically valuable dihydropyrimidine derivative. This compound serves as a critical advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel dihydropyrimidine-based drug candidates, particularly for cardiovascular and neurological applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new active pharmaceutical ingredients (APIs).
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of complex heterocyclic libraries for high-throughput screening.
• Academic & Institutional R&D: Employed in university and research institute laboratories for studying enzyme inhibition mechanisms and developing new synthetic methodologies.

Basic Information

Item	Information
Product Name	2-Methoxyethyl 6-Methyl-2-Oxo-4-(4-Propoxyphenyl)-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate
CAS No.	330848-24-3
Molecular Formula	C18H22N2O5
Molecular Weight	346.38 g/mol
Synonyms	2-Methoxyethyl 4-(4-propoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 6-Methyl-2-oxo-4-(4-propoxyphenyl)-1,4-dihydropyrimidine-5-carboxylic acid 2-methoxyethyl ester; 4-(4-Propoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid 2-methoxyethyl ester; DHPM derivative; Biginelli reaction product; Dihydropyrimidinone ester
EINECS	Contact for details

Quality Control

Our 2-Methoxyethyl 6-Methyl-2-Oxo-4-(4-Propoxyphenyl)-3,4-Dihydro-1H-Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.