Description

6-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in active pharmaceutical ingredient (API) development and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the research of kinase inhibitors due to its quinazoline-pyrimidine hybrid structure.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Biochemical Research: Used as a tool compound in biochemical assays to study enzyme interactions and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	6-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One
CAS No.	330830-77-8
Molecular Formula	C₁₇H₁₇N₅O
Molecular Weight	307.35 g/mol
Synonyms	6-Methyl-2-[(4,6,8-trimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone; 2-((4,6,8-Trimethylquinazolin-2-yl)amino)-6-methylpyrimidin-4(3H)-one; 330830-77-8; 6-Methyl-2-((4,6,8-trimethylquinazolin-2-yl)amino)pyrimidin-4-ol; 4(3H)-Pyrimidinone, 6-methyl-2-[(4,6,8-trimethyl-2-quinazolinyl)amino]-
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-2-[(4,6,8-Trimethylquinazolin-2-Yl)Amino]Pyrimidin-4(3H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistency and reliability for critical research applications. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.