Description

n-Benzyl-2-[(4-Oxo-3-Phenyl-5,6,7,8-Tetrahydro-[1]Benzothiolo[2,3-D]Pyrimidin-2-Yl)Sulfanyl]Acetamide is a sophisticated heterocyclic organic compound featuring a fused benzothienopyrimidine core, which is of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical pharmacophore and synthetic intermediate for creating novel bioactive agents, particularly in oncology and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Probe Development: Serves as a starting material for creating labeled compounds used in assay development and target validation.
• Academic Research: Employed in university and institutional labs for investigating new chemical entities and their biological mechanisms.
• Preclinical Candidate Synthesis: Integral to the production of compounds for in vitro and in vivo efficacy and toxicity studies.
• Custom Synthesis Projects: Supplied to partners requiring bespoke, high-purity intermediates for proprietary drug discovery pipelines.

Basic Information

Product Name	n-Benzyl-2-[(4-Oxo-3-Phenyl-5,6,7,8-Tetrahydro-[1]Benzothiolo[2,3-D]Pyrimidin-2-Yl)Sulfanyl]Acetamide
CAS No.	329921-07-5
Molecular Formula	C27H23N3O2S2
Molecular Weight	493.62 g/mol
Synonyms	2-[(4-Oxo-3-phenyl-5,6,7,8-tetrahydro[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(phenylmethyl)acetamide; N-Benzyl-2-((4-oxo-3-phenyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide; Benzothieno[2,3-d]pyrimidine acetamide derivative; CAS 329921-07-5; 329921-07-5; BTOPA; 2-[(3-Phenyl-4-oxo-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio]-N-(phenylmethyl)acetamide
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. Purity is typically confirmed to be ≥95% by HPLC, with specifications tailored to client requirements. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Single impurity ≤ 1.0%; Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.