Description

5-(3,4-Dichlorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for medicinal chemistry research and development, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical companies focused on developing new small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel pyrazolopyrimidine-based active pharmaceutical ingredients (APIs) for therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs targeting various disease pathways.
• Agrochemical Development: Serves as a building block for creating new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-(3,4-Dichlorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	329212-64-8
Molecular Formula	C14H6Cl2F3N3O2
Molecular Weight	376.12 g/mol
Synonyms	5-(3,4-Dichlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 7-(Trifluoromethyl)-5-(3,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-; CAS 329212-64-8; 5-(3,4-Dichlorophenyl)-7-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 329212-64-8
EINECS	Contact for details

Quality Control

Our 5-(3,4-Dichlorophenyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. All batches undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing comprehensive specifications. We adhere to cGMP principles where applicable to support our clients in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.