Description

H-Arg-Arg-Gly-Asp-Met-Glu-Oh CAS NO 328946-37-8 is a synthetic hexapeptide sequence containing the Arg-Gly-Asp (RGD) motif, a critical recognition site for integrin receptors. This compound is of significant value in biochemical and pharmaceutical research for studying cell adhesion, signaling pathways, and as a potential lead structure in therapeutic development. It is primarily utilized by researchers and developers in the fields of biomedical research, drug discovery, and diagnostic assay development.

Application

• Biomedical Research: As a key reagent for studying integrin-mediated cell adhesion, migration, and signaling in cancer, angiogenesis, and wound healing models.
• Drug Discovery: Serves as a reference standard and a scaffold for developing novel anti-thrombotic, anti-angiogenic, or anti-cancer therapeutics targeting integrins.
• Diagnostic Development: Used in the development of assays and biosensors to detect specific integrin expression or activity.
• Biomaterial Functionalization: Coating material for surfaces to promote or inhibit specific cell attachment in tissue engineering and implant design.
• Biochemical Tool: Competitive inhibitor in studies to characterize integrin-ligand interactions and receptor specificity.

Basic Information

Product Name	H-Arg-Arg-Gly-Asp-Met-Glu-Oh
CAS No.	328946-37-8
Molecular Formula	C27H48N14O10S
Molecular Weight	760.83 g/mol
Synonyms	Arg-Arg-Gly-Asp-Met-Glu; RGD-Met-Glu Peptide; H-Arg-Arg-Gly-Asp-Met-Glu-OH; Hexapeptide RGD Sequence; Integrin-binding peptide; Adhesion motif peptide; RRGDME; Cyclo(RGDfK) analogue precursor; Cell adhesion peptide
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Arg-Arg-Gly-Asp-Met-Glu-Oh undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed specifications for purity, content, and impurity profiles to ensure consistency and reliability for your research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Assay (Content)	≥ 98%
Amino Acid Composition	Conforms to theoretical
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.