Description

8-Chloro[1]Benzofuro[3,2-D]Pyrimidin-4(3H)-One is a high-value heterocyclic organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique fused benzofuropyrimidine scaffold makes it a versatile building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, where its fused ring system can influence charge transport properties.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in heterocyclic chemistry and the discovery of new chemical entities.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized dyes and pigments with specific light-absorption characteristics.

Basic Information

Product Name	8-Chloro[1]Benzofuro[3,2-D]Pyrimidin-4(3H)-One
CAS No.	328277-09-4
Molecular Formula	C10H5ClN2O2
Molecular Weight	220.61 g/mol
Synonyms	8-Chloro-1-benzofuro[3,2-d]pyrimidin-4(3H)-one; 8-Chloro-3H-[1]benzofuro[3,2-d]pyrimidin-4-one; 328277-09-4; 8-Chlorobenzofuro[3,2-d]pyrimidin-4(3H)-one; 8-Chloro-1-benzofuro[3,2-d]pyrimidin-4-ol; 4H-Benzofuro[3,2-d]pyrimidin-4-one, 8-chloro-; 8-Chloro-4-hydroxy[1]benzofuro[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 8-Chloro[1]Benzofuro[3,2-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.