Description

Pyr-Gly-Gly-Leu-Arg-Trp-NH2 is a synthetic hexapeptide amide, a sequence of pyroglutamic acid, glycine, glycine, leucine, arginine, and tryptophan. This compound is of significant interest in biochemical and pharmaceutical research due to its potential role as a substrate or inhibitor in enzymatic studies and as a building block for more complex peptide structures. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in proteomics, drug discovery, and peptide synthesis.

Application

• Biochemical Research: Used as a reference standard or substrate in enzyme kinetics studies, particularly for proteases and peptidases.
• Pharmaceutical Development: Serves as a key intermediate or a pharmacophore model in the design and synthesis of novel therapeutic peptides.
• Proteomics & Diagnostics: Employed in the development of assay kits and diagnostic tools for detecting specific enzymatic activities.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships and signal transduction pathways.
• Peptide Library Synthesis: Acts as a core sequence for generating focused libraries to screen for biological activity.

Basic Information

Product Name	Pyr-Gly-Gly-Leu-Arg-Trp-NH2
CAS No.	328085-50-3
Molecular Formula	C34H51N11O8
Molecular Weight	741.85 g/mol
Synonyms	Pyroglutamyl-Glycyl-Glycyl-Leucyl-Arginyl-Tryptophanamide; pGlu-Gly-Gly-Leu-Arg-Trp-NH2; H-pGlu-Gly-Gly-Leu-Arg-Trp-NH2; Pyr-Gly-Gly-Leu-Arg-Trp-Amid; CAS 328085-50-3; Hexapeptide-1 (related); Research Peptide 328085-50-3
EINECS	Contact for details

Quality Control

Our Pyr-Gly-Gly-Leu-Arg-Trp-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full transparency and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.