Description

L-Proline, 4-(2-Aminoethyl)-, (4R)- (9Ci) is a non-proteinogenic, chiral amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel bioactive molecules and therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and neurology.
• Peptidomimetic Synthesis: Used to construct constrained peptide analogs and macrocycles to enhance metabolic stability and receptor selectivity.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or organocatalysts in enantioselective synthesis.
• Biochemical Research: Utilized in studies of enzyme inhibition, receptor-ligand interactions, and metabolic pathway analysis.
• Agrochemical Development: Serves as an intermediate in the synthesis of novel, chiral active ingredients for crop protection.
• Academic Research: A valuable tool for synthetic organic chemists exploring new methodologies and complex molecular architectures.

Basic Information

Product Name	L-Proline, 4-(2-Aminoethyl)-, (4R)- (9Ci)
CAS No.	327989-68-4
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(4R)-4-(2-Aminoethyl)-L-proline; (2S,4R)-4-(2-Aminoethyl)pyrrolidine-2-carboxylic acid; 4-(2-Aminoethyl)-L-proline; L-4-(2-Aminoethyl)proline; (4R)-AEP; 4-(2-Aminoethyl)proline; (2S,4R)-4-(2-Aminoethyl)proline; 327989-68-4
EINECS	Contact for details

Quality Control

Our L-Proline, 4-(2-Aminoethyl)-, (4R)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.