Description

Boc-D-Lys(Aloc)-Oh Dcha is a protected amino acid derivative, specifically the D-isomer of lysine with orthogonal protecting groups. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control and selective deprotection strategies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-lysine residues into peptide chains, enabling the study of structure-activity relationships.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, including antimicrobial peptides, hormone analogs, and targeted drug delivery conjugates.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter molecules due to its orthogonal Aloc (Allyloxycarbonyl) protecting group.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds with modified peptide backbones.
• Biochemical Tool Development: Essential for creating enzyme substrates, inhibitors, and probes where the specific stereochemistry of lysine is required.

Basic Information

Product Name	Boc-D-Lys(Aloc)-Oh Dcha
CAS No.	327156-94-5
Molecular Formula	C₂₀H₃₆N₂O₆ • C₁₄H₂₃N
Molecular Weight	548.71 g/mol (Free acid), 721.98 g/mol (DCHA salt)
Synonyms	Boc-D-Lys(Aloc)-OH DCHA salt; Nα-(tert-Butoxycarbonyl)-Nε-(allyloxycarbonyl)-D-lysine dicyclohexylamine salt; (2R)-6-{[(Prop-2-en-1-yloxy)carbonyl]amino}-2-{[(tert-butoxycarbonyl)amino]hexanoic acid - N,N-dicyclohexylamine (1:1); Boc-D-Lys(Aloc)-OH • DCHA; DCHA salt of Boc-D-Lys(Aloc)-OH; N(epsilon)-Allyloxycarbonyl-N(alpha)-Boc-D-lysine DCHA salt; Protected D-Lysine derivative.
EINECS	Contact for details

Quality Control

Our Boc-D-Lys(Aloc)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.