Description

H-Ala(3-Pyridyl)-Ome·2Hcl is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of alanine substituted with a 3-pyridyl group. This compound serves as a crucial building block (synthon) in advanced organic synthesis, particularly for the construction of complex peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based active pharmaceutical ingredients (APIs) and therapeutic candidates.
• Peptidomimetic Research: Used to introduce the 3-pyridyl-alanine moiety into peptide backbones to modulate bioactivity, stability, and receptor binding properties.
• Chemical Biology Probes: Employed in the development of labeled peptides and molecular probes for studying biological pathways and protein interactions.
• Combinatorial Chemistry: A valuable building block in solid-phase and solution-phase peptide synthesis libraries for high-throughput screening.
• Agrochemical Synthesis: Potential intermediate in the development of advanced crop protection agents with peptide-like structures.

Basic Information

Product Name	H-Ala(3-Pyridyl)-Ome·2Hcl
CAS No.	327051-07-0
Molecular Formula	C9H13Cl2N2O2
Molecular Weight	252.12 g/mol
Synonyms	H-3-Pal-OMe·2HCl; Methyl (S)-2-amino-3-(pyridin-3-yl)propanoate dihydrochloride; L-3-Pyridylalanine methyl ester hydrochloride; 3-(3-Pyridyl)-L-alanine methyl ester dihydrochloride; (S)-2-Amino-3-(3-pyridyl)propionic acid methyl ester hydrochloride; Ala(3-Pyridyl)-OMe hydrochloride; H-L-3-Pal-OMe·2HCl
EINECS	Contact for details

Quality Control

Our production of H-Ala(3-Pyridyl)-Ome·2Hcl adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.