Description

5-Pyrimidinepropanoic Acid, α-Aminohexahydro-1-Methyl-2,4-Dioxo-, (Alphas,5R)- (9Ci) is a high-purity, stereochemically defined pyrimidine derivative. This compound is a critical chiral building block and intermediate in advanced pharmaceutical synthesis, valued for its structural complexity and functional groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel antiviral and anticancer drug candidates.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to introduce the pyrimidinepropanoic acid moiety into target molecules.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and route optimization for the manufacture of high-value fine chemicals.
• Biochemical Research: Potential use as a substrate or inhibitor in enzymatic studies due to its structural similarity to natural pyrimidine bases.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary compounds for specialized applications.

Basic Information

Product Name	5-Pyrimidinepropanoic Acid, α-Aminohexahydro-1-Methyl-2,4-Dioxo-, (Alphas,5R)- (9Ci)
CAS No.	326891-10-5
Molecular Formula	C8H13N3O4
Molecular Weight	215.21 g/mol
Synonyms	(2S,5R)-2-Amino-1-methyl-5-(2-carboxyethyl)hexahydropyrimidine-4,6-dione; (αS,5R)-α-Aminohexahydro-1-methyl-2,4-dioxo-5-pyrimidinepropanoic Acid; 5-Pyrimidinepropanoic acid, α-aminohexahydro-1-methyl-2,4-dioxo-, (αS,5R)-; (S,R)-enantiomer of the pyrimidinepropanoic acid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinepropanoic Acid derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.