Description

5-Pyrimidinepropanoic Acid, α-Aminohexahydro-1-Methyl-2,4-Dioxo-, (Alphas,5S)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its complex molecular architecture, which incorporates multiple functional groups suitable for constructing sophisticated pharmacophores. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel antiviral, anticancer, or central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Research: Serves as a sophisticated building block in the synthesis of new-generation herbicides, fungicides, or insecticides with targeted modes of action.
• Chemical Biology Probe Development: Used to create labeled or modified compounds for studying enzyme mechanisms, protein-ligand interactions, and metabolic pathways.
• Peptidomimetic Synthesis: Its amino acid-like structure makes it valuable for constructing non-peptide scaffolds that mimic peptide function for drug discovery.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Custom Synthesis Starting Material: Provides a complex, multi-functional core for custom manufacturing and scale-up projects requiring specific stereochemistry.

Basic Information

Item	Details
Product Name	5-Pyrimidinepropanoic Acid, α-Aminohexahydro-1-Methyl-2,4-Dioxo-, (Alphas,5S)- (9Ci)
CAS No.	326891-09-2
Molecular Formula	C8H13N3O4
Molecular Weight	215.20 g/mol
Synonyms	(2S,5S)-2-Amino-5-methyl-1,3-diazinane-4,6-dione-2-propanoic acid; (αS,5S)-α-Aminohexahydro-1-methyl-2,4-dioxo-5-pyrimidinepropanoic acid; Hexahydro-1-methyl-2,4-dioxo-5-pyrimidinepropanoic acid, α-amino-, (αS,5S)-; A chiral dihydrouracil derivative; (S,S)-enantiomer of amino-dihydropyrimidinepropionic acid
EINECS	Contact for details

Quality Control

Every batch of our 5-Pyrimidinepropanoic Acid, α-Aminohexahydro-1-Methyl-2,4-Dioxo-, (Alphas,5S)- (9Ci) is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, which are critical for research and development reproducibility. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and related substances is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.