Description

N4-Benzoyl-1-[[2-Hydroxy-1-(Hydroxy Methyl)Ethoxy] Methyl]Cytosine is a key nucleoside derivative and a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling the precise construction of modified oligonucleotides and nucleotide analogs, where it serves to protect the cytosine base during sensitive coupling reactions. This compound is essential for research and development laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on antisense therapeutics, diagnostic probes, and novel antiviral agents. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used as a protected phosphoramidite monomer in solid-phase synthesis of DNA and RNA sequences for research and therapeutic applications.
• Prodrug Development: Serves as a precursor in the design of prodrugs to enhance the bioavailability and targeting of nucleotide analogs.
• Biochemical Research: Employed in studies investigating nucleic acid chemistry, enzyme mechanisms, and gene function.
• Diagnostic Probe Manufacturing: A key raw material for producing labeled nucleotides used in diagnostic assays and sequencing technologies.

Basic Information

Product Name	N4-Benzoyl-1-[[2-Hydroxy-1-(Hydroxy Methyl)Ethoxy] Methyl]Cytosine
CAS No.	326802-60-2
Molecular Formula	C17H19N3O6
Molecular Weight	361.35 g/mol
Synonyms	1-[(2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl]-N4-benzoylcytosine; 1-[(2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl]-N-benzoylcytosine; N4-Benzoyl-1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]cytosine; 1-(2-Hydroxy-1-hydroxymethylethoxymethyl)-N4-benzoylcytosine; Bz-Cytosine Glyceryl Derivative; Protected Cytosine Glyceryl Monomer; Cytosine, N-benzoyl-1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl]-
EINECS	Contact for details

Quality Control

Our N4-Benzoyl-1-[[2-Hydroxy-1-(Hydroxy Methyl)Ethoxy] Methyl]Cytosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive pharmaceutical R&D. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable, and our quality systems are designed to meet the stringent requirements of advanced intermediate supply for the global life sciences market.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; therefore, containers should be kept sealed in a dry environment to prevent moisture uptake, which could affect stability and performance in sensitive synthetic applications.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.