Description

4-Chloro-5-Methyl-2-(Methylsulfonyl)Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the reactive chloromethyl and methylsulfonyl groups, which enable precise molecular modifications for creating complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of potential drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to construct complex molecular architectures.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials, such as ligands for catalysts or monomers for polymers.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratory settings.

Basic Information

Product Name	4-Chloro-5-Methyl-2-(Methylsulfonyl)Pyrimidine
CAS No.	325780-94-7
Molecular Formula	C6H7ClN2O2S
Molecular Weight	206.65 g/mol
Synonyms	2-(Methylsulfonyl)-4-chloro-5-methylpyrimidine; 4-Chloro-5-methyl-2-methylsulfonylpyrimidine; 4-Chloro-5-methylpyrimidine-2-sulfonylmethane; Pyrimidine, 4-chloro-5-methyl-2-(methylsulfonyl)-; 325780-94-7
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-2-(Methylsulfonyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, from research to cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.