Description

6-Bromo-2-(4-(2-Chlorophenyl)Piperazin-1-Yl)-4-Phenylquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting specific receptor pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• CNS Drug Development: Employed in the research of compounds targeting neurological disorders, leveraging its piperazine and quinazoline pharmacophores.
• Kinase Inhibitor Synthesis: Acts as a scaffold for developing novel kinase inhibitors, a major class in oncology and anti-inflammatory therapeutics.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Item	Details
Product Name	6-Bromo-2-(4-(2-Chlorophenyl)Piperazin-1-Yl)-4-Phenylquinazoline
CAS No.	324759-78-6
Molecular Formula	C24H20BrClN4
Molecular Weight	479.80 g/mol
Synonyms	6-Bromo-2-[4-(2-chlorophenyl)-1-piperazinyl]-4-phenylquinazoline; 2-(4-(2-Chlorophenyl)piperazin-1-yl)-6-bromo-4-phenylquinazoline; 324759-78-6; UNII-9K3F8S5F5H; 4-Phenyl-6-bromo-2-[4-(2-chlorophenyl)-1-piperazinyl]quinazoline; Quinazoline, 6-bromo-2-[4-(2-chlorophenyl)-1-piperazinyl]-4-phenyl-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(4-(2-Chlorophenyl)Piperazin-1-Yl)-4-Phenylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.