Description

2-(Benzylthio)-5,6,7,8-Tetrahydro-[1]-Benzothieno[2,3-D]Pyrimidin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Used in the research and development of potential kinase inhibitors due to its privileged pyrimidine-based structure.
• Medicinal Chemistry: Employed as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology: Utilized as a probe or tool compound for studying biological processes and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and APIs.

Basic Information

Product Name	2-(Benzylthio)-5,6,7,8-Tetrahydro-[1]-Benzothieno[2,3-D]Pyrimidin-4(1H)-One
CAS No.	324036-21-7
Molecular Formula	C19H18N2OS2
Molecular Weight	354.49 g/mol
Synonyms	2-(Benzylthio)-4-oxo-1,4,5,6,7,8-hexahydrobenzothieno[2,3-d]pyrimidine; 4(1H)-Benzothieno[2,3-d]pyrimidinone, 5,6,7,8-tetrahydro-2-[(phenylmethyl)thio]-; 2-Benzylsulfanyl-5,6,7,8-tetrahydro-1H-benzothieno[2,3-d]pyrimidin-4-one; 324036-21-7; THBT-BZTPO; BTT-Pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-(Benzylthio)-5,6,7,8-Tetrahydro-[1]-Benzothieno[2,3-D]Pyrimidin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.