Description

L-Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-4-[[[(4S)-Hexahydro-2,6-Dioxo-4-Pyrimidinyl]Carbonyl]Amino]- is a sophisticated, high-purity protected amino acid derivative designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex organic synthesis, particularly in the development of novel pharmaceuticals and bioactive peptides. It serves as an essential intermediate for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of modified phenylalanine residues.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the development of targeted therapeutics.
• Process Chemistry: Serves as a critical intermediate in the scalable production of active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the creation of peptide-drug conjugates and other labeled biomolecules for diagnostic and therapeutic use.
• Chemical Biology Probes: Used to synthesize probes for studying enzyme mechanisms and protein-protein interactions.

Basic Information

Product Name	L-Phenylalanine, n-[(1,1-Dimethylethoxy)Carbonyl]-4-[[[(4S)-Hexahydro-2,6-Dioxo-4-Pyrimidinyl]Carbonyl]Amino]-
CAS No.	324017-29-0
Molecular Formula	C21H26N4O6
Molecular Weight	430.46 g/mol
Synonyms	Boc-Phe(4-NH-DHP)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((((4S)-hexahydro-2,6-dioxo-4-pyrimidinyl)carbonyl)amino)phenyl)propanoic acid (related protected form); N-Boc-4-[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl)carboxamido]-L-phenylalanine; Fmoc-Phe(4-DHP)-OH (alternative protecting group); 4-[[[(4S)-Hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanine, N-Boc protected; Boc-L-Phenylalanine(4-(N-(4S)-2,6-dioxohexahydro-4-pyrimidinyl))amide; Protected L-Phenylalanine DHP derivative.
EINECS	Contact for details

Quality Control

Our L-Phenylalanine derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.