Description

Fsl-1 Lipoprotein, Synthetic is a high-purity, synthetic toll-like receptor 2 (TLR2) agonist designed for advanced immunological research and development. This compound is critical for studying innate immune responses, macrophage activation, and inflammatory signaling pathways. It is an essential reagent for researchers and developers in the fields of immunology, vaccine adjuvants, and novel therapeutic discovery.

Application

• Immunological Research: Used as a potent and specific agonist for Toll-like Receptor 2 (TLR2) to study innate immune system activation and signaling cascades.
• Vaccine Adjuvant Development: Serves as a key component in preclinical research for evaluating novel adjuvant systems designed to enhance vaccine efficacy.
• Inflammation Studies: Applied in cellular assays to model and investigate inflammatory responses, cytokine production, and macrophage polarization.
• Drug Discovery Screening: Utilized in high-throughput screening (HTS) platforms to identify and validate new anti-inflammatory or immunomodulatory compounds.
• Cell Culture & Stimulation: Employed to stimulate immune cells such as dendritic cells, monocytes, and macrophages in vitro for functional studies.
• Biodefense & Pathogen Research: Acts as a synthetic mimic of bacterial lipoproteins to study host-pathogen interactions and defense mechanisms.

Basic Information

Item	Detail
Product Name	Fsl-1 Lipoprotein, Synthetic
CAS No.	322455-70-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fsl-1; Pam2CGDPKHPKSF; S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoyl-(R)-cysteinyl-glycyl-aspartyl-prolyl-lysyl-histidyl-prolyl-lysyl-seryl-phenylalanine; Synthetic TLR2 Agonist; TLR2 Ligand FSL-1; Fibroblast-Stimulating Lipopeptide 1; N-Palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]-(R)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe
EINECS	Contact for details

Quality Control

Our Fsl-1 Lipoprotein, Synthetic is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, endotoxin levels, and biological activity is provided with every shipment to support your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/mg
Biological Activity (Cell-Based Assay)	Conforms
Water Content (KF)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.