Description

Pth (73-84) (Human) is a synthetic peptide fragment corresponding to residues 73-84 of the human parathyroid hormone. This high-purity peptide reference standard is critical for research and development in endocrinology and metabolic bone disease studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic kit manufacturers for assay development, calibration, and quality control. The compound is supplied with full analytical characterization to ensure reliable and reproducible experimental results.

Application

• Biomedical Research: Used as a precise reference standard in studies investigating the structure, function, and signaling pathways of parathyroid hormone (PTH).
• Assay Development & Validation: Critical for the calibration and quality control of immunoassays (e.g., ELISA, RIA) designed to detect PTH or related fragments in biological samples.
• Pharmaceutical R&D: Serves as a key intermediate or reference material in the discovery and development of novel therapeutics targeting calcium homeostasis and bone metabolism.
• Diagnostic Manufacturing: Employed in the production and lot-to-lot verification of clinical diagnostic kits for measuring PTH levels, aiding in the diagnosis of hyperparathyroidism and hypoparathyroidism.
• Antibody Production: Acts as a specific immunogen for generating monoclonal or polyclonal antibodies targeted against defined epitopes within the PTH molecule.
• Peptide Mapping: Utilized in mass spectrometry and chromatographic studies for the identification and characterization of PTH and its metabolites.

Basic Information

Product Name	Pth (73-84) (Human)
CAS No.	321957-35-1
Molecular Formula	C58H95N19O19
Molecular Weight	1326.5 g/mol
Synonyms	Parathyroid Hormone (73-84), human; PTH (73-84); hPTH (73-84); Parathyrin (73-84); H-Val-Lys-Lys-Asp-Asn-Val-Asn-Val-Leu-Thr-Lys-Ala-OH; H-VKKDNVNVLTKA-OH; PTH Fragment 73-84
EINECS	Contact for details

Quality Control

Every batch of Pth (73-84) (Human) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for HPLC purity, peptide content, amino acid analysis, and mass spectrometry. We adhere to cGMP guidelines for the production of peptide reference standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below in a dry environment. Once reconstituted, aliquot and store solutions at -20°C or -80°C to minimize freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (K.F.)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.