Description

L-Phenylalanine,n-((9H-Fluoren-9-Ylmethoxy)Carbonyl)-β-Meth CAS NO 321524-83-8 is a protected amino acid derivative, specifically an Fmoc (9-fluorenylmethoxycarbonyl)-protected L-phenylalanine analog with a β-methyl modification. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-purity, sequence-specific intermediates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid monomer for the automated, sequential construction of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including metabolic regulators, hormone analogs, and targeted therapeutics.
• Bioconjugation and Probe Development: Serves as a modified precursor for creating fluorescently labeled or affinity-tagged peptides for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Employed to generate diverse arrays of peptide compounds for high-throughput screening against biological targets.
• Academic & Institutional Research: Fundamental reagent for studying protein structure-function relationships, enzyme kinetics, and molecular recognition processes.
• Biomaterials Engineering: A component in the design of bio-inspired polymers, hydrogels, and surface coatings with specific biological activities.

Basic Information

Item	Details
Product Name	L-Phenylalanine,n-((9H-Fluoren-9-Ylmethoxy)Carbonyl)-β-Meth
CAS No.	321524-83-8
Molecular Formula	C26H25NO5
Molecular Weight	431.48 g/mol
Synonyms	Fmoc-β-Me-Phe-OH; Fmoc-β-Methyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-methyl-L-phenylalanine; (2S)-3-Phenyl-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid; Fmoc-L-β-methylphenylalanine; Fmoc-β-methyl-Phe; Protected β-methylphenylalanine; Fmoc-β-Me-Phe
EINECS	Contact for details

Quality Control

Our Fmoc-protected amino acids are manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including HPLC for purity and chiral integrity, and is supplied with a detailed Certificate of Analysis (COA). We support compliance with cGMP guidelines for advanced intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.