Description

Benzenemethanamine, 3,4-Difluoro-α-Methyl-, (Alphas)- (9Ci) is a chiral, fluorinated benzylamine derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a stereogenic center with fluorine atoms to modulate the physicochemical and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and bioavailability. The CAS number for this product is 321318-17-6.

Application

This fluorinated chiral amine serves as a critical intermediate in the synthesis of complex molecules. Its primary applications include:

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutics.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the fluorine atoms and chiral center contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, enabling more efficient and selective synthetic routes.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Diagnostic Reagent Building Block: Utilized in the synthesis of probes and markers for imaging and diagnostic applications.

Basic Information

Product Name	Benzenemethanamine, 3,4-Difluoro-α-Methyl-, (Alphas)- (9Ci)
CAS No.	321318-17-6
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	(αS)-α-Methyl-3,4-difluorobenzylamine; (S)-1-(3,4-Difluorophenyl)ethanamine; (S)-α-Methyl-3,4-difluorobenzylamine; (S)-3,4-Difluoro-α-methylbenzylamine; 321318-17-6; (S)-1-(3,4-Difluorophenyl)ethylamine; (S)-(-)-α-Methyl-3,4-difluorobenzylamine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, 3,4-Difluoro-α-Methyl-, (Alphas)- (9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, GC, and NMR, to ensure it meets the exacting standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from incompatible materials such as strong oxidizing agents, acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee, HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.