Description

2,4,5-Trifluoro-1,3-phenylenediamine is a fluorinated aromatic diamine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluoro substitution pattern on the benzene ring. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and target binding.
• Polymer & Material Science: Serves as a monomer for producing high-performance polyimides, polyamides, and other fluorinated polymers with enhanced thermal stability and chemical resistance.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Manufacturing: Acts as a starting material for synthesizing advanced fluorinated dyes and pigments with unique color fastness and optical properties.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for exploring new chemical entities.

Basic Information

Product Name	2,4,5-Trifluoro-1,3-Phenylenediamine
CAS No.	321182-37-0
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	1,3-Diamino-2,4,5-trifluorobenzene; 2,4,5-Trifluorobenzene-1,3-diamine; 2,4,5-Trifluoro-m-phenylenediamine; 2,4,5-Trifluoro-1,3-benzenediamine; 2,4,5-Trifluoro-1,3-diaminobenzene; 3,4,6-Trifluorobenzene-1,3-diamine; 321182-37-0 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-1,3-phenylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthesis applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.